principal investigators

COMMISSARIAT A L’ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES – CEA-LIST

neurocare-bergonzoDr Philippe Bergonzo, Eur.Ing, PhD, HDR, 44, is research Director at CEA with expertise in the field of diamond research. Since 2003, he leads a research team with 25 researchers now called the Diamond Sensors Laboratory. He has supervised PhDs and MSc students and is currently supervising 2 PhD students. He is the scientific coordinator of several national (MEDINAS, DIATHERM and IMPLANTS) and European (FP6-NMP DREAMS Diamond on Retinal Micro-Interface Structures) projects. Moreover, he recently was the coordinator of 2 bilateral projects, currently running with AIST in Japan (2008-2009) and the Institute of Physics of Prague (2009-2010). In addition, he is the author of 180 articles in scientific journals and has attended as author over 80 meetings and international conferences. He has been invited to 25 international conferences and is a member of several diamond conference committees and editorial scientific committees. He has an H-index of 23 (01/12/2010) and holds 4 patents.
neurocare-scorsoneDr. Emmanuel Scorsone holds a PhD in Instrumentation and Analytical Science from UMIST, Manchester. He gained expertise in chemical sensors, while working on the development of various chemical sensor technologies as an academic researcher and in industry. He joined the CEA-LIST laboratory in 2006 where he leads development activities related to chemical sensors and analytical systems. He is involved in many EU and national projects related to smart diamond based systems for various applications ranging from health to security. In particular, he coordinates two large technical work packages in the EU FP7-Security projects, Nanosecure and Ditsef. He has gained skills in IP management from working in industry as well as in the Technical Research division of CEA for many years. He is co-author of more than 20 scientific papers and 4 patents in the area of chemical sensing and implantable devices.
neurocare-girardHugues GIRARD graduated from the University of Versailles, France, in 2008 with a PhD in Chemistry and Materials Science. During his PhD, he worked on the electrochemical reactivity of diamond electrodes according to their surface chemistry. From 2008 to 2010, he took on a postdoctoral position at the CEA and the Ecole Polytechnique (France). He gained expertise in the chemical preparation and functionalization of diamond nanoparticles. At this time, he developed new approaches for the dispersion of diamond nanoparticles onto a substrate, to enhance CVD polycrystalline diamond growth. Combining nanodiamonds surface chemistry and electrostatic interactions, he elaborated a new technique allowing homogeneous diamond growth on 3D structures. Since 2010, he is a permanent staff member at the Diamond Sensor Laboratory, CEA-LIST, where his research interests relate mainly to the biological and technological applications of diamond nanoparticles. He is co-author of more than 15 papers in peer-reviewed, international journals and gave 13 communications in international conferences.
neurocare-merChristine MER, graduated with a master “Synthesis and characterization of thin film materials”. She joined the CEA-LIST in 1999 as research engineer and gained expertise in the growth of synthetic diamond by MPCVD (Microwave Plasma Chemical Vapour deposition). The first years, she worked on the development of diamond detectors for nuclear industrial applications (alpha, X, gamma and neutrons detection). Since 2004, she has developed new research projects (French projects ANR and European projects) focused on the study and optimization of boron doped growth conditions on homoepitaxial and polycrisatalline diamond.

COMMISSARIAT A L’ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES – CEA-CLINATEC

neurocare-benabidDr. Alim-Louis Benabid is Scientific Director of CEA-CLINATEC and Professor of Neurobiophysics at Joseph Fourier University. He received his MD in 1970 and became Assistant in Neurosurgery, University Hospital Grenoble. He received a PhD in Physics en 1972 and then became Prof. of Experimental Medicine and Surgery and Head of Neurosurgery. Since 2004, he has served as Head of Functional Neurosurgery. He was also Coordinator of the Center for Functional Neurosurgery “Claudio Munari”, Milano, Italy and Staff Consultant at the Cleveland Clinic Foundation, Cleveland, USA. He is a member of the National Committee for Neurosurgery 2001-present (Nominated by the Minister of Education). He has won several honors and prizes: Scientific Award 2000-International Neurobionics Foundation (Hannover); Prize “Joachim Zulch” of the Gertrud Reemstma Foundation, Koln Germany; Cotzias Award, Spanish Society of Neurology, Barcelona; Milton Shy Award, NIH-Philadelphia- Columbia New York; Sherrington Medal of the Royal Society of Medicine, London; Prize “Recherche et Santé” of the “Institut des Sciences et de la Santé”; Prize “Betty and David Koetser Foundation” (Zurich), Prize “Dingebauer” of the German Society of Neurology (Manheim), Doctor Honoris Causa, University of Algiers, Algeria, Spiegel and Wycis Medal of the World Federation of Functional and Stereotactic Societies. He is member of the “Académie de Médecine”, Chevalier de l’Ordre National de la Légion d’Honneur, Member of the Royal Academy of Medicine of Belgium, and Member of the “Académie des Sciences” at “Institut de France”.
neurocare-sauter staraceDr. Fabien Sauter-Starace is Project Manager and Research Engineer. He received his PhD in Mechanics and Material Science in 2000, before becoming a senior scientist at Corning FRC in the field of MEMS and BioMEMS design and packaging. From 2002 to 2008, he was in charge of several lab-on-chip and Medical device projects at the CEA-LETI, such as the Neurolink project. He became an early member of CLINATEC and is now in charge of the technological development concerning biocompatible packaging and microtechnologies. Number of publications: 16, number of patents: 9.
neurocare-ratelDr. David Ratel is a Neurobiologist, Expert in histological studies in CLINATEC. He obtained his PhD degree in Neuroscience in 2002 before joining the Montreal Centre for Experimental Therapeutics in Cancer. He authored and co-authored 18 scientific publications and 2 patents.

ESIEE-PARIS

neurocare-lissorguesGaëlle Lissorgues has a full professor position at ESIEE. She obtained her diploma from the Ecole Normale Supérieure of Cachan in Applied Physics in 1993 (Agregation of Applied physics, 1st), and taught courses at the University Pierre et Marie Curie of Paris VI. She got her PhD of the University Paris VI, in Electrical Engineering in 1997 and she obtained the “Habilitation à Diriger les Recherches” from University Marne-La-Vallée in October 2006. She currently is a member of ESYCOM and Research Director for several Research students and 3 PhD students training. She has published more than 20 papers in international journals, 50 papers in international conferences with proceedings, and 4 patents related to MEMS. Moreover, she has been an invited researcher in the Paris Vision Institute from September 2009 to July 2010 in the team of S. Picaud and J. Sahel, to improve the interface between engineer and biomedical staff in the frame of several common projects.
Lionel Rousseau, completed his PhD at University Paris-Est January 2010 in after pursuing an engineering degree at CNAM (Conservatoire National des Arts et Métiers). He joined ESIEE-PARIS-Paris in 2001 to work in clean room as a process engineer. While he initially committed to the development of MEMS, in 2003 he oriented his activities towards new applications of micro-technologies to Biosciences, especially Neurosciences where he has developed new processes to realize 3D micro needle array (MEA Micro Electrode Array). He is involved in several national French research projects in the field of technology for medical applications like retinal implant and development of MEA for neural tissues stimulation and recording. Today he follows two PhD students. He has published 6 papers in international journals, more than 15 papers in international conferences with proceedings, and holds 3 patents related to MEMS. In December 2010, he was rewarded the « Engineer of the Year of Innovation » Award by theUsine NouvelleIndustrie et Technologies and Ingénieurs et scientifiques de France.

FORSCHUNGSZENTRUM JUELICH GMBH – JUELICH

neurocare-offenhausserProf. Dr. Andreas Offenhäusser studied physics and completed his PhD dissertation in 1989 at the University of Ulm. For 2 years, he worked in the field of power transistors at Robert Bosch GmbH in Reutlingen, Germany. From 1992 until 1994 he performed a post doctoral study at the Frontier Research Program at RIKEN, Japan. Afterwards, he worked as a group leader at the Max-Planck-Institute for Polymer Research in Mainz, Germany. Since 2001, Prof. Offenhäusser is director of the Peter-Gruenberg Institut/Institute of Complex Systems at the Forschungszentrum JUELICH and Professor of Experimental Physics at the Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen. His current research is focused on the use of electronic materials for applications in biosensing and bioelectronics. He has coordinated one EU integrated project and authored/coauthored more than 150 200 scientific publications. He holds several patents and is the Head of the clean room facility at the Forschungszentrum JUELICH.
neurocare-maybeckVanessa Maybeck studied Biotechnology at the University of Stonybrook, New York 2000-2004. She then received her MPhil in BioScience Enterprise from the University of Cambridge, UK. Her Dr. rer. nat. is from the Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen in biology. She is currently a post doctoral researcher at the Forschungszentrum Juelich GmbH working on optogenetics and bioelectronics. In addition, Vanessa worked as a research associate for 6 years and has worked as a biotechnology industry consultant during internships with Cambridge Antibody Technology and Rufus Scientific Ltd., both UK firms.

QWANE BIOSCIENCES SA – QWANE

neurocare-heuschkelDr. Marc Heuschkel, CEO holds a PhD in Micro-engineering from the Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland, where he developed 3D tip-shaped MEA biochips. This development improved the extra-cellular recording technique for acute tissue slice experimentation allowing tight coupling between active cells inside the tissue slice and the recording/stimulating electrodes. During this work, he gained experience in microsystem manufacturing and assembly technologies that are required for low-cost MEA fabrication. In addition, he carried out biological experiments on acute hippocampal tissue slices for 3D MEA validation. He was the coordinator of the EU-FP7 PharMEA project (FP7-SME-2008-232554) that aimed to develop a novel MEA recording and stimulation platform (up to 1024 electrodes in parallel integrating real-time data analysis features) for industrial pharmacology and toxicology drug screening. His work deals mainly with development of new customized MEA biochips as well as fabrication and sales of MEA biochips.

UNIVERSITY COLLEGE LONDON – UCL

neurocare-jackmanProf. Richard B. Jackman: Head of the Diamond Electronics Group within LCN at UCL, he holds the Chair in Electronic Devices. Richard is also the Director of UCL’s Masters programme in Nanotechnology. Having earned his PhD in the field of Surface Science (University of Southampton, 1986), Prof. Jackman moved to the University of Oxford where he was the Royal Society Eliz. Challenor Research Fellow (1986-89) and Junior Research Fellow of Linacre College in Oxford. Upon his arrival at UCL in 1989, Richard initiated research into the application of CVD diamond for devices, a new field to the University in 1990. He was then promoted to a Senior Lectureship (1992), Readership (1996) and to the Chair in Electronic Devices (2008). Richard has given around 60 invited talks at international meetings and has published over 160 journal papers and over 200 conference papers, in addition to 4 patents. Prof. Jackman has acted as a consultant to a number of EU companies, has been the Vice-Chair of the Electronic Materials and Processing division within IUVSTA (1998-2001), UK Councillor to IUVSTA (2001-4) and Chair of the British Vacuum Council (BVC, 200-3). Conference organisation has included Co-Chairing the series of Symposia entitled ‘Diamond Electronics and Biotechnology: Fundamentals to Applications’ I, II, III and V within the MRS Fall conference (Boston USA, 2006, 7, 9, 11).
Dr. Robert Edgington. Following completion of a masters degree in in physics and biophysics at Oxford University 2003-2007, Robert graduated from UCL in 2011 with a PhD in Electrical Engineering with a thesis specialising in the application of diamond at the brain machine interface. Currently Robert is a postdoctoral researcher in the Jackman laboratory at UCL developing brain machine interface devices using nanodiamond coatings.

UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ – UM

neurocare-kempskiProf. Oliver Kempski, Director of Inst. Neurosurgical Pathophysiology. Prof. Kempski is an expert in experimental surgery/neurosurgery. He has led three German Research Foundation and one Federal Ministry of Education and Research projects and authored/coauthored more than 190 scientific publications. He holds one patent and is the Head of the university animal experiment ethics committee.
neurocare-heimannDr. Axel Heimann, a veterinary surgeon with more than 20 years experience in experimental surgery/neurosurgery. He has authored/coauthored more than 100 scientific publications.
Dr. Andree Shalabi, Dr. Andree Shalabi earned her PhD in medicine and has extensive experience in the field of neuroscience, neurology and neurosurgery. Since 2001 she works additionally as instructor for the US State Dep and was active at different institutions like the University of Chicago or the Weizmann Institute in Rehovot, Israel.

OBELIA SARL – MXM

Jean Louis DIVOUX, 53, received his Dipl – Ing (IDPE) degree from ENSERG (Grenoble) with an electronics specialization. He joined MXM laboratories in 1989 in the R&D dept. of integration and miniaturization of Active Implantable Medical Devices (AIMD) and in particular cochlear implants. His long experience in design of AIMD has given him knowledge of regulatory affairs, FES electrode conception, biomaterial selection and machining, tests and reliability of AIMD. He was responsible for providing the SUAW project (EU – BIOMED 2: BMH4961501) with the implantable receivers-stimulators. He is member of the joint working group developing the EN 45502-2-5 standard on cochlear implant systems and he participates in the review of EN 45502-1 standard on AIMD. He is now project manager in OBELIA. He participates in and leads numerous National and Europeans R&D projects.

NANO RETINA LTD – NR

neurocare-gefenRa’anan Gefen received a B.Sc. in Extended Physics and Mathematics. It was awarded in 1983 by the Hebrew University, Jerusalem, as part of the prestigious TALPIOT program, an elite Israeli Defense Forces training program. Ra’anan obtained his MBA in International Management, Finance and investments and Technological management from the Recanati Faculty for Business Administration at Tel-Aviv University, Israel, in 1997. Leading the Nano-Retina initiative, Ra’anan is well known in both the defense and medical industries for his expertise in developing and managing large scale, multi-discipline, highly innovative R&D projects, based on a system engineering approach. Prior to his position at Nano-Retina, Ra’anan served as EVP and acting CEO at GiView Ltd. and as CTO at Vascular Dynamics Ltd. Ra’anan has been issued a US patent for a “Fully-implantable cardiac recovery system.” During his career, Ra’anan dealt with multi-million dollar projects involving a variety of partners from all around the world.
neurocare-benhaimLaura Benhaim received a B.Sc. degree in Orthoptics and worked in an eye Clinic in Paris, France, where she performed electrophysiology, functional ophthalmological explorations, retinal imaging and rehabilitation for visual impaired patients. In the same time, she obtained the M.Sc. in reeducation and medical engineering, specialization: clinical research in re-education, from Pierre & Marie Curie University in Paris, France. She imported from Israel a new technology and developed successfully the use of a new rehabilitation method for amblyopia in adult patients. Ms. Benhaim’s research activity concerns the ophthalmology, brain plasticity and visual neurosciences in visual rehabilitation techniques and devices. In 2010, she collaborated with the CNRS in Paris where she worked on developing a follow-up protocol for anisometropic amblyopia in adult. She is now responsible of the ophthalmological research in Nano Retina Ltd.
neurocare-haneinProf. Yael Hanein received the B.Sc. degree in physics from Tel-Aviv University, Israel, and the M.Sc. and Ph.D. degrees in physics from the Weizmann Institute of Science, Israel. In 2003, she completed a Postdoctoral Fellowship at the Electrical Engineering Department and a research associate position at the Physics Department at the University of Washington, Seattle and joined the faculty of Tel-Aviv University. She is currently an Associate Professor at the school of Electrical Engineering at Tel-Aviv University and a VP at NR. Prof. Hanein’s research activity concerns the development of electronic nano devices, in those designed to interface with brain cells and to record their activity. These devices have far reaching applications in the realm of understanding brain disorders, the effect of drugs on the brain and the possibility to build implantable electronic brain chips. She also co-directs the Tel-Aviv University nano and micro central characterization and fabrication facility, a prototyping facility currently servicing over 30 academic research groups and over 20 companies. Prof. Hanein has authored over 45 journal papers and presented over 50 invited talks and seminars worldwide. Prof. Hanein teaches undergraduate and graduate level classes at Tel-Aviv University. She is an APS member and an IEEE senior member.

UNIVERSITE PIERRE ET MARIE CURIE – PARIS 6 – UPMC – Institut de la Vision (Paris)

neurocare-sahelProf. José Sahel focuses his clinical and research activities on currently untreatable retinal diseases. He is the Director of the Institut de la Vision (250 staff); Professor of Ophthalmology at UPMC, and the Cumberlege Professor of Biomedical Sciences at the Institute of Ophthalmology, UCL. He chairs a department of ophthalmology at the Quinze-Vingts National Ophthalmology Hospital and at the Rothschild Ophthalmology Foundation and coordinates the Ophthalmology Clinical Investigation Centre and the National Reference Centre for Retinal Dystrophies. Prof. Sahel was a Visiting Lecturer at Harvard Medical School, Visiting Professor at the U. of Wisconsin, Madison, and Professor of Ophthalmology at Louis Pasteur U., Strasbourg. He lead the development of innovative therapies for protecting retinal photoreceptors, and identifying a key mechanism and family of proteins involved in the maintenance of cone-mediated central and light-adapted vision. He is co-author of over 200 papers and several patents. He coordinated large scale European Research programs on retinal functional genomics, neuroprotection, ageing, and therapy, as well as a European network of over 50 clinical trial centres on retinal diseases. A member or chair of several scientific boards (Inserm, University, Alcon Research Institute, etc), he advises biotechs and larger companies. He co-founded Fovea Pharmaceuticals. He received several awards for his teams’ achievements (e.g. Foundation Fighting Blindness (FFB) Trustee Award, Grand Prix NRJ-Neurosciences-Institut de France, Alcon Research Institute Award for Excellence in Vision Research, Foundation Altran Innovation Award, Honoris Causa Doctorate of the University of Geneva, Switzerland, etc).
neurocare-picaudDr. Serge Picaud is the Head of the Department of Visual Information Processing. He graduated from the Ecole Normale Supérieure of Cachan in biochemistry, obtained his PhD degree in Neurosciences and then his habilitation. He worked with Prof. Wässle (Max Planck Institute for Brain Research) and Prof. Werblin (U. California, Berkeley), two eminent specialists in retinal physiology and anatomy. He collaborates frequently with industry and co-founded the start up company, Fovea Pharmaceuticals, later bought by Sanofi-Aventis. He co-created the PVI. Partner of 4 European projects (2 ongoing), he co-authored over 60 scientific publications and holds 10 patents. He discovered the cause of the retinal toxicity of the anti-epileptic drug, vigabatrin, the first line drug for the treatment of infantile spasms. He is a member of the scientific committee for the French Federation of Blind and Visually Impaired Patients and a member of the administrative committee for the French See and Hear Foundation.

TECHNISCHE UNIVERSITAET MUENCHEN – TUM

neurocare-garridoDr. Jose A. Garrido: head of the Functional Carbon Materials group at the Walter Schottky Institute, Technische Universität München (TUM) He received a PhD degree in Telecommunication Engineering from the Technical University of Madrid (UPM), Spain in 2000. Later, he moved to the WSI, where he is now an Assistant Professor and permanent stuff of the TUM. His current research focuses on the use of carbon-based functional materials, such as diamond, graphene, and organic semiconductors for applications in biosensing and bioelectronics. He served as principal investigator in 6 German, and 4 international projects. He coauthored more than 75 scientific publications. He has co-organized numerous international conferences on diamond and graphene. Currently, he is Editor of Diamond and Related Materials.
neurocare-stutzmannProf. Martin Stutzmann: director of Walter Schottky Institute. He received a PhD in physics from the University of Marburg and completed a Postdoc at the Xerox Palo Alto Research Center. From 1985 to 1993, he was part of the permanent research staff at the Max-Planck-Institute for Solid State Research, Stuttgart. In 1988, he received the Walter Schottky Prize of the German Physical Society. Since 1993 he is full professor at TUM. Currently, he is director of the Walter Schottky Institut and Dean of the Physics Department of the TUM. He is one of the key figures of the European research on the a-Si, III-V nitrides devices and heterojunctions and nanoelectronics. He has coauthored more than 500 scientific publications, and published numerous book chapters.

KURL SALMON LUXEMBOURG S.A. – KS

neurocare-santosMartinho Santos Silva holds a Bachelor degree in Business and Administration studies with major in Finance and International Management. Since 2006, he is responsible for the development of the « Financial Subsidy Services » department of Kurt Salmon in several countries. Martinho is an expert in assisting companies in securing and managing European grants and incentives for their projects. He has also a long-track experience in the management of projects funded within FP7.
neurocare-trimbourJean Trimbour holds an Engineering degree (French / Spanish degree) and has over 10 years of experience in European programmes. He participated in the setting-up, the negotiation and management of several European research projects in the FP7 programme (up to 18 partners, 17 M€ budget).

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE – CNRS-INCIA

neurocare-yvertDr. Blaise Yvert obtained his Master of Engineering in Applied Physics from Ecole Centrale de Lyon and Cornell University in 1993 and his PhD degree in Biomedical Engineering from INSA Lyon in 1996. Until 2002, he studied functional brain imaging using electro- and magneto-encephalography at Inserm U280 Lyon. His research focused on source localization methods from scalp EEG/MEG and intracerebral EEG data and the use of these methods to map the spatiotemporal dynamics of human cortical auditory areas. In 2003, he then moved to the study of neural network dynamics using MEA. He moved to Bordeaux, where he initiated the development of large-scale microelectrode array technology (MEAs) for dynamic recording and stimulation of neural networks. From then, his work aims at developing new MEA technologies through several collaborations, as well as dedicated tools for the analysis of MEA data. He is also deeply interested in understanding the mechanisms underlying extracellular neural microstimulation and optimizing stimulating MEA devices. These systems are then used experimentally to study the dynamics of developing neural networks, and to develop rehabilitation strategies of the injured CNS. He has coordinated 2 national collaborative projects on MEA developments and is involved in 4 others. He authored or co-authored 27 international peer-reviewed articles and 3 patent applications.

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